Partial hydrolysis of a synthetic heptapeptide related to gramicidin S.
نویسندگان
چکیده
منابع مشابه
Partial proof of Graham Higman's conjecture related to coset diagrams
Graham Higman has defined coset diagrams for PSL(2,ℤ). These diagrams are composed of fragments, and the fragments are further composed of two or more circuits. Q. Mushtaq has proved in 1983 that existence of a certain fragment γ of a coset diagram in a coset diagram is a polynomial f in ℤ[z]. Higman has conjectured that, the polynomials related to the fragments are monic and for a fixed degree...
متن کاملPermeability of dormant spores of Bacillus subtilis to gramicidin S.
Gramicidin S, dissolved in ethanol, penetrated into the inside of the dormant spores of Bacillus subtilis, had a partial inhibitory effect on L-alanine-initiated germination and completely inhibited their outgrowth and vegetative growth. The activity of particulate NADH oxidase of the antibiotic-treated dormant spores was also influenced significantly. Abnormal morphological changes were observ...
متن کاملNovel cycloundecapeptides related to gramicidin S with both high antibiotic activity and low hemolytic activity.
To find candidates with high antimicrobial and low hemolytic activities, many gramicidin S (GS) analogs of various ring sizes have been designed and synthesized. However, syntheses of antimicrobially active analogues of GS having a disordered symmetry structure from C(2) have almost never been reported, because the stable, amphiphilic β-sheet structure of GS with C(2) symmetry is considered ess...
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Several amino acids are known to affect the gramicidin S producer Bacillus brevis ATCC 9999 with respect ot growth, soluble gramicidin S synthetase formation, antibiotic production, or a combination of these. Our studies confirmed that arginine has paradoxical effects on the B. brevis fermentation; it markedly increased growth and antibiotic production, yet decreased the soluble heavy gramicidi...
متن کاملThe free amino group of gramicidin S.
on the other hand, maintain that both amino and carboxyl groups are present and that the 8-amino group of the ornithine residue is not free. Their evidence for this latter point, nevertheless, is not very convincing and the problem was clearly one which could be readily settled by applying the new dinitrofluorobenzene (DNFB) method (Sanger, 1945). Accordingly at Dr Synge's suggestion, the prese...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1980
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.44.1941